Corectin® tablets contain ivermectin which is an ecto-endoparasiticide in nature. It is also effective against both external and internal parasites. Ivermectin causes flaccid paralysis of parasites by interacting with GABA and glutamate-gated channels.
Corectin is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Corectin is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.
Corectin, a type of medication known as a beta-blocker, is used to treat high blood pressure. Beta-blockers lower blood pressure by decreasing the force and rate of heart contractions, which reduces the heart’s demand for oxygen. Corectin can be used alone or in combination with other high blood pressure medications.
Use Corectin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Corectin is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension. Corectin is structurally similar to metoprolol, acebutolol and atenolol in that it has two substituents in the para position of the benzene ring. The β1-selectivity of these agents is thought to be due in part to the large substituents in the para position. At lower doses (less than 20 mg daily), Corectin selectively blocks cardiac β1-adrenergic receptors with little activity against β2-adrenergic receptors of the lungs and vascular smooth muscle. Receptor selectivity decreases with daily doses of 20 mg or greater. Unlike propranolol and pindolol, Corectin does not exhibit membrane-stabilizing or sympathomimetic activity. Corectin possesses a single chiral centre and is administered as a racemic mixture. Only l-Corectin exhibits significant β-blocking activity.
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